Table 2.
Mortality in the Testosterone-Treated and Untreated Groups Over the Follow-Up Period.
| ID | Start of Therapy | Time of Death/Event | Treatment Duration, Months | Comorbidities | Baseline T Levels | End Point T Levels | Baseline IIEF-EF | End Point IIEF-EF | Cause of Death |
|---|---|---|---|---|---|---|---|---|---|
| Testosterone Group (n = 2) | |||||||||
| 184 | 2008 | April 2015 | 72 | Crohn’s disease, ED | 9.7 | 18.7 | 17 | 26 | Postsurgical thromboembolism |
| 247 | 2010 | May 2015 | 54 | Osteoporosis, T2DM | 10.1 | 18.0 | 23 | 29 | Traffic accident |
| Control group (n = 21) | |||||||||
| 1 | 2009 | October 2015 | 66 | Osteoporosis, T2DM, MI, CAD, ED | 10.7 | 7.3 | 20 | 12 | Lung embolism |
| 31 | 2007 | September 2015 | 90 | T2DM, CAD, ED | 7.3 | 6.2 | 22 | 7 | MI |
| 278 | 2009 | November 2012 | 30 | T2DM, MI, CAD, ED | 7.3 | 6.2 | 13 | 7 | Stroke |
| 279 | 2010 | October 2013 | 30 | T1DM, Stroke, ED | 10.1 | 6.2 | 14 | 6 | MI |
| 280 | 2008 | November 2012 | 42 | MI, CAD, ED | 10.7 | 7.6 | 13 | 6 | Heart failure |
| 281 | 2009 | March 2013 | 36 | T2DM, Stroke, CAD, ED | 11.4 | 8.3 | 11 | 8 | Pneumonia and lung failure |
| 282 | 2008 | April 2012 | 36 | T1DM, Stroke, CAD, ED | 9.0 | 8.7 | 13 | 9 | MI |
| 283 | 2009 | December 2013 | 42 | MI, ED | 10.7 | 8.7 | 14 | 8 | Thromboembolism |
| 284 | 2007 | February 2011 | 36 | Stroke, ED | 9.7 | 9.7 | 12 | 9 | Heart failure |
| 285 | 2010 | November 2014 | 42 | MI, ED | 10.1 | 8.0 | 11 | 8 | MI |
| 286 | 2011 | September 2014 | 30 | T2DM, CAD, ED | 10.4 | 9.4 | 13 | 7 | Thromboembolism |
| 287 | 2007 | February 2010 | 24 | T2DM, CAD, ED | 9.4 | 10.1 | 12 | 9 | Heart failure |
| 288 | 2009 | May 2013 | 36 | T1DM, Stroke, CAD, ED | 9.7 | 7.3 | 14 | 6 | Renal failure |
| 289 | 2006 | December 2009 | 36 | MI, Stroke, ED | 9.4 | 9.7 | 12 | 7 | Heart failure |
| 290 | 2007 | March 2011 | 48 | T2DM, Stroke, CAD, ED | 10.1 | 9.4 | 13 | 9 | MI |
| 291 | 2007 | June 2010 | 36 | CAD, ED | 9.7 | 9.7 | 12 | 8 | Thromboembolism |
| 292 | 2009 | March 2013 | 36 | MI, CAD, ED | 10.1 | 8.3 | 14 | 6 | Stroke |
| 293 | 2006 | July 2010 | 42 | Stroke, CAD, ED | 11.1 | 8.7 | 13 | 7 | Heart failure |
| 294 | 2007 | December 2013 | 66 | T2DM, MI, Stroke, CAD, ED | 11.4 | 9.4 | 12 | 7 | Stroke |
| 295 | 2006 | January 2012 | 60 | T2DM, CAD, ED | 10.4 | 10.1 | 15 | 6 | Heart failure |
| 296 | 2009 | March 2015 | 60 | T2DM, MI, CAD, ED | 10.1 | 9.7 | 13 | 8 | Stroke |
Abbreviations: CAD, coronary artery disease; ED, erectile dysfunction; IIEF-EF, International Index of Erectile Function, Erectile Function domain; MI, myocardial infarction; T1DM, diabetes mellitus type 1; T2DM, diabetes mellitus type 2.