Table 1. GST values for HMDP strains over repeated-flurothyl seizures.
Strain | GST1 Mean | GST1 SE | GST2 Mean | GST2 SE | GST3 Mean | GST3 SE | GST4 Mean | GST4 SE | GST5 Mean | GST5 SE | GST6 Mean | GST6 SE | GST7 Mean | GST7 SE | GST8 Mean | GST8 SE | GST Retest Mean | GST Retest SE | Kindling Mean | Kindling SE |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
129S1/SvImJ | 356 | 21 | 410 | 10 | 425 | 28 | 379 | 18 | 368 | 23 | 335 | 29 | 312 | 11 | 364 | 5 | −9 | 1 | ||
129X1/SvJ | 440 | 14 | 406 | 20 | 394 | 21 | 405 | 50 | 325 | 43 | 298 | 39 | 368 | 12 | 394 | 48 | −9 | 6 | ||
A/J | 397 | 57 | 519 | 7 | 402 | 98 | 351 | 91 | 421 | 99 | 425 | 153 | 422 | 110 | 586 | 68 | 621 | 21 | 4 | 31 |
Balb/cJ | 338 | 22 | 365 | 23 | 323 | 35 | 356 | 24 | 382 | 15 | 332 | 21 | 306 | 22 | 327 | 25 | 320 | 8 | −5 | 3 |
BTBRT<+>tf/J | 340 | 10 | 343 | 17 | 358 | 13 | 360 | 8 | 365 | 19 | 380 | 9 | 321 | 16 | 334 | 19 | 246 | 13 | −1 | 3 |
BXD1/TyJ | 291 | 8 | 283 | 11 | 243 | 10 | 210 | 7 | 204 | 9 | 195 | 8 | 192 | 14 | 183 | 12 | 170 | 11 | −16 | 2 |
BXD100/RwwJ | 314 | 29 | 300 | 11 | 282 | 7 | 274 | 11 | 241 | 15 | 240 | 11 | 214 | 18 | 205 | 17 | 218 | 7 | −16 | 4 |
BXD11/TyJ | 357 | 14 | 321 | 10 | 325 | 9 | 292 | 12 | 270 | 7 | 260 | 16 | 245 | 11 | 248 | 5 | 270 | 17 | −17 | 2 |
BXD12/TyJ | 375 | 12 | 289 | 8 | 281 | 9 | 257 | 8 | 228 | 9 | 187 | 5 | 238 | 8 | 220 | 10 | 189 | 15 | −20 | 2 |
BXD13/TyJ | 405 | 25 | 367 | 8 | 312 | 14 | 298 | 15 | 232 | 16 | 217 | 16 | 175 | 12 | 234 | 16 | 231 | 35 | −30 | 2 |
BXD14/TyJ | 409 | 7 | 384 | 18 | 275 | 10 | 311 | 18 | 247 | 7 | 277 | 15 | 255 | 12 | 234 | 22 | 243 | 22 | −22 | 2 |
BXD15/TyJ | 269 | 12 | 264 | 12 | 247 | 17 | 203 | 16 | 202 | 15 | 209 | 12 | 207 | 13 | 218 | 22 | 200 | 23 | −9 | 2 |
BXD16/TyJ | 391 | 9 | 307 | 9 | 298 | 14 | 258 | 13 | 253 | 13 | 238 | 9 | 230 | 16 | 224 | 12 | 191 | 4 | −21 | 3 |
BXD18/TyJ | 516 | 36 | 399 | 28 | 379 | 37 | 324 | 9 | 291 | 14 | 262 | 13 | 243 | 4 | 254 | 14 | 240 | 19 | −36 | 3 |
BXD19/TyJ | 411 | 17 | 423 | 50 | 327 | 30 | 306 | 10 | 320 | 36 | 299 | 22 | 265 | 30 | 314 | 38 | 275 | 33 | −18 | 6 |
BXD2/TyJ | 426 | 23 | 350 | 10 | 304 | 13 | 330 | 18 | 317 | 22 | 314 | 21 | 317 | 20 | 305 | 27 | 286 | 21 | −9 | 3 |
BXD20/TyJ | 426 | 16 | 330 | 18 | 292 | 18 | 289 | 20 | 281 | 20 | 273 | 16 | 262 | 13 | 267 | 19 | 296 | 13 | −18 | 2 |
BXD21/TyJ | 473 | 18 | 315 | 14 | 258 | 5 | 235 | 10 | 259 | 10 | 238 | 15 | 263 | 15 | 265 | 10 | 268 | 18 | −21 | 2 |
BXD22/TyJ | 395 | 5 | 370 | 7 | 331 | 5 | 346 | 12 | 254 | 36 | 339 | 19 | 326 | 7 | 291 | 11 | 381 | 2 | −12 | 1 |
BXD24/TyJ | 330 | 21 | 304 | 12 | 266 | 22 | 299 | 13 | 303 | 9 | 303 | 12 | 286 | 8 | 265 | 12 | 321 | 7 | −5 | 3 |
BXD27/TyJ | 366 | 20 | 361 | 15 | 326 | 8 | 320 | 12 | 304 | 12 | 310 | 15 | 284 | 9 | 285 | 9 | 290 | 6 | −12 | 2 |
BXD28/TyJ | 342 | 15 | 363 | 17 | 296 | 11 | 280 | 18 | 268 | 18 | 253 | 9 | 232 | 17 | 247 | 8 | 284 | 30 | −17 | 2 |
BXD29/TyJ | 469 | 8 | 394 | 19 | 352 | 19 | 331 | 9 | 325 | 13 | 290 | 28 | 260 | 24 | 270 | 22 | 257 | 20 | −27 | 2 |
BXD31/TyJ | 359 | 19 | 295 | 12 | 247 | 9 | 209 | 17 | 198 | 17 | 197 | 15 | 178 | 17 | 168 | 21 | 193 | 27 | −25 | 4 |
BXD32/TyJ | 318 | 7 | 265 | 11 | 268 | 9 | 288 | 15 | 265 | 17 | 259 | 6 | 257 | 9 | 256 | 20 | 216 | 17 | −6 | 2 |
BXD33/TyJ | 501 | 19 | 398 | 19 | 309 | 16 | 262 | 15 | 233 | 7 | 216 | 10 | 217 | 9 | 221 | 8 | 286 | 12 | −38 | 3 |
BXD34/TyJ | 454 | 18 | 285 | 16 | 258 | 3 | 229 | 12 | 220 | 11 | 219 | 12 | 234 | 13 | 233 | 13 | 205 | 25 | −23 | 2 |
BXD36/TyJ | 269 | 12 | 227 | 10 | 190 | 10 | 196 | 5 | 202 | 8 | 215 | 10 | 222 | 6 | 218 | 13 | 227 | 30 | −4 | 2 |
BXD38/TyJ | 377 | 10 | 338 | 10 | 268 | 10 | 234 | 8 | 217 | 6 | 219 | 15 | 193 | 18 | 172 | 11 | 247 | 21 | −28 | 2 |
BXD39/TyJ | 410 | 19 | 377 | 13 | 363 | 14 | 305 | 13 | 320 | 10 | 335 | 16 | 332 | 14 | 340 | 13 | 259 | 19 | −9 | 2 |
BXD40/TyJ | 371 | 5 | 324 | 10 | 262 | 9 | 236 | 17 | 179 | 14 | 193 | 18 | 212 | 20 | 199 | 16 | 276 | 40 | −24 | 2 |
BXD42/TyJ | 398 | 22 | 314 | 14 | 284 | 16 | 264 | 12 | 249 | 17 | 225 | 10 | 248 | 11 | 228 | 11 | 178 | 13 | −20 | 3 |
BXD43/RwwJ | 363 | 9 | 325 | 41 | 352 | 13 | 349 | 31 | 283 | 10 | 289 | 16 | 264 | 32 | 292 | 12 | 317 | 3 | −13 | 3 |
BXD44/RwwJ | 295 | 15 | 279 | 14 | 274 | 14 | 259 | 17 | 264 | 25 | 245 | 19 | 210 | 10 | 207 | 10 | 300 | 7 | −12 | 2 |
BXD48/RwwJ | 393 | 11 | 354 | 25 | 345 | 17 | 345 | 21 | 343 | 20 | 331 | 25 | 235 | 9 | 251 | 16 | 253 | 13 | −19 | 3 |
BXD49/RwwJ | 391 | 37 | 289 | 17 | 288 | 18 | 286 | 27 | 288 | 10 | 261 | 18 | 283 | 17 | 259 | 20 | 269 | 17 | −12 | 3 |
BXD5/TyJ | 293 | 10 | 263 | 14 | 243 | 11 | 222 | 5 | 242 | 11 | 229 | 8 | 229 | 11 | 226 | 15 | 176 | 12 | −10 | 2 |
BXD50/RwwJ | 345 | 23 | 308 | 20 | 214 | 18 | 243 | 9 | 252 | 10 | 256 | 18 | 248 | 23 | 236 | 12 | 268 | 21 | −11 | 3 |
BXD51/RwwJ | 363 | 9 | 309 | 16 | 265 | 39 | 220 | 24 | 207 | 25 | 200 | 1 | 228 | 15 | 254 | 23 | 211 | 31 | −16 | 2 |
BXD55/RwwJ | 422 | 99 | 388 | 23 | 208 | 16 | 246 | 40 | 208 | 19 | 218 | 7 | 188 | 12 | 191 | 5 | 334 | 111 | −31 | 6 |
BXD56/RwwJ | 375 | 17 | 345 | 28 | 312 | 25 | 297 | 19 | 198 | 30 | 301 | 25 | 170 | 40 | 243 | 21 | 196 | 26 | −23 | 3 |
BXD6/TyJ | 463 | 13 | 442 | 44 | 436 | 48 | 377 | 38 | 367 | 43 | 287 | 22 | 263 | 8 | 241 | 10 | 303 | 24 | −16 | 5 |
BXD60/RwwJ | 313 | 9 | 306 | 19 | 229 | 15 | 271 | 18 | 281 | 10 | 309 | 12 | 247 | 22 | 211 | 13 | 273 | 21 | −9 | 2 |
BXD61/RwwJ | 296 | 8 | 268 | 10 | 253 | 16 | 261 | 23 | 251 | 22 | 204 | 4 | 197 | 34 | 223 | 28 | 128 | 12 | −12 | 2 |
BXD62/RwwJ | 281 | 14 | 309 | 18 | 316 | 16 | 261 | 12 | 256 | 1 | 269 | 5 | 240 | 24 | 241 | 23 | 214 | 30 | −9 | 4 |
BXD64/RwwJ | 298 | 17 | 267 | 32 | 285 | 17 | 283 | 12 | 279 | 21 | 222 | 23 | 158 | 27 | 215 | 3 | 229 | 23 | −16 | 4 |
BXD65/RwwJ | 387 | 14 | 356 | 9 | 407 | 23 | 356 | 12 | 366 | 23 | 318 | 22 | 295 | 14 | 319 | 16 | 335 | 24 | −12 | 1 |
BXD68/RwwJ | 375 | 14 | 337 | 16 | 334 | 12 | 359 | 10 | 310 | 23 | 316 | 15 | 356 | 12 | 328 | 34 | 368 | 30 | −4 | 4 |
BXD73/RwwJ | 389 | 12 | 322 | 22 | 277 | 24 | 273 | 8 | 233 | 15 | 262 | 14 | 238 | 11 | 219 | 9 | 263 | 25 | −20 | 3 |
BXD75/RwwJ | 377 | 15 | 310 | 29 | 322 | 23 | 315 | 15 | 326 | 20 | 268 | 31 | 303 | 10 | 348 | 17 | 326 | 18 | −5 | 4 |
BXD8/TyJ | 276 | 12 | 250 | 14 | 207 | 14 | 229 | 22 | 194 | 12 | 188 | 13 | 188 | 14 | 178 | 7 | 209 | 5 | −13 | 2 |
BXD87/RwwJ | 400 | 34 | 287 | 12 | 288 | 33 | 220 | 15 | 229 | 14 | 220 | 19 | 212 | 10 | 200 | 11 | 224 | 14 | −23 | 4 |
BXD9/TyJ | 370 | 15 | 346 | 12 | 323 | 12 | 304 | 13 | 283 | 11 | 234 | 13 | 238 | 14 | 220 | 12 | 303 | 8 | −21 | 2 |
BXD98/RwwJ | 306 | 18 | 310 | 29 | 234 | 17 | 266 | 17 | 250 | 10 | 234 | 9 | 251 | 19 | 219 | 10 | 273 | 21 | −11 | 2 |
C3H/HeJ | 553 | 51 | 473 | 87 | 575 | 330 | 241 | 213 | 297 | 392 | −35 | |||||||||
C57BL/10J | 405 | 24 | 352 | 20 | 294 | 14 | 259 | 12 | 242 | 11 | 267 | 9 | 254 | 11 | 252 | 9 | 271 | 9 | −19 | 3 |
C57BL/6J | 424 | 9 | 353 | 9 | 291 | 6 | 256 | 6 | 238 | 10 | 211 | 6 | 217 | 9 | 218 | 7 | 229 | 10 | −28 | 1 |
C57BL/6NJ | 326 | 17 | 311 | 14 | 284 | 11 | 239 | 12 | 237 | 10 | 234 | 9 | 235 | 7 | 241 | 15 | 230 | 5 | −13 | 3 |
C57BLKS/J | 281 | 7 | 280 | 17 | 243 | 7 | 244 | 16 | 216 | 6 | 209 | 6 | 203 | 6 | 201 | 9 | 194 | 6 | −13 | 1 |
Cast/EiJ | 448 | 21 | 463 | 45 | 325 | 24 | 275 | 28 | 240 | 32 | 303 | 50 | 210 | 20 | 235 | 23 | 309 | 61 | −34 | 4 |
CBA/J | 351 | 15 | 301 | 15 | 272 | 19 | 250 | 16 | 252 | 16 | 238 | 15 | 227 | 17 | 245 | 16 | 258 | 32 | −15 | 2 |
CE/J | 384 | 10 | 416 | 22 | 323 | 17 | 263 | 14 | 275 | 13 | 255 | 33 | 217 | 17 | 182 | 19 | 228 | 22 | −31 | 4 |
DBA/2J | 265 | 13 | 241 | 11 | 233 | 9 | 224 | 12 | 252 | 12 | 258 | 17 | 257 | 14 | 210 | 19 | 180 | 19 | −4 | 3 |
FVB/NJ | 280 | 13 | 263 | 14 | 259 | 10 | 248 | 10 | 225 | 11 | 236 | 9 | 227 | 11 | 239 | 9 | 227 | 17 | −7 | 3 |
LG/J | 508 | 10 | 441 | 19 | 385 | 18 | 352 | 12 | 345 | 20 | 294 | 7 | 290 | 9 | 282 | 8 | 337 | 15 | −32 | 2 |
MRL/Mpj | 397 | 40 | 379 | 21 | 337 | 15 | 321 | 23 | 311 | 27 | 285 | 12 | 287 | 24 | 265 | 6 | 331 | 26 | −18 | 3 |
NOD/LtJ | 317 | 6 | 322 | 9 | 309 | 11 | 307 | 15 | 320 | 12 | 295 | 16 | 287 | 15 | 298 | 17 | 285 | 14 | −6 | 3 |
NZW/LacJ | 385 | 19 | 401 | 20 | 366 | 25 | 323 | 19 | 348 | 17 | 322 | 11 | 354 | 11 | 331 | 9 | 282 | 16 | −9 | 2 |
PWD/PhJ | 338 | 8 | 293 | 30 | 320 | 10 | 297 | 18 | 289 | 9 | 251 | 13 | 243 | 14 | 243 | 18 | 233 | 19 | −16 | 4 |
Sm/J | 357 | 10 | 324 | 20 | 348 | 8 | 367 | 15 | 316 | 11 | 310 | 10 | 286 | 9 | 302 | 11 | 309 | 6 | −8 | 3 |
Average | 373 | 18 | 337 | 19 | 304 | 17 | 286 | 17 | 271 | 18 | 263 | 17 | 252 | 16 | 257 | 16 | 262 | 20 | −16 | 3 |
h2 | 0.55 | 0.71 | 0.54 | 0.75 | 0.70 | 0.79 | 0.62 | 0.36 | 0.50 | 0.94 |