Table 2. Top five SNP associations for kindling, GST1, GST6, and retest GST.
| Phenotype | Position (bp)a | −logP | SNP ID | M.A.F.b | Flanking Genes Within 500 kb of SNPc |
|---|---|---|---|---|---|
| Kindling | 1:174420753 | 5.86E−09 | rs3707910 | 0.1433 | Igfs8, Atp1a2, Kcnj9, Kcnj10, Pigm, Igsf9, Slamf9, Tafln2, Cfap45, Slamf8, Fcrl6, Dusp23, Crp |
| 1:175151112 | 5.86E−09 | rs8242481 | 0.182 | Olfr1408, Olfr1406, Olfr218, Mptx2, Olfr1404, Olfr418, Ackr1, Cadm3, Aim2, Gm4995 | |
| 1: 174797513 | 6.06E−09 | rs30463665 | 0.25 | Dusp23, Crp, Apcs, SNORA17, Olfr16 | |
| 1: 176533310 | 1.40E−08 | rs2020486 | 0.22 | Olfr417, Olfr248, Olfr414, olfr220, Fmn2 | |
| 1: 174239958 | 1.41E−08 | rs30472229 | 0.25 | Copa, Pex19, Dcaf8, Pea15a, Casaq1, Igfs8, Atp1a2, Kcnj9, Kcnj10, Pigm | |
| GST day 1 | 1: 174420753 | 3.15E−06 | rs3707910 | 0.143 | Igfs8, Atp1a2, Kcnj9, Kcnj10, Pigm, Igsf9, Slamf9, Tagln2, Cfap45, Slamf8, Fcrl6, Dusp23 |
| 1: 175151112 | 3.15E−06 | rs8242481 | 0.182 | Olfr16, Olfr1408, Olfr1406, Olfr218, Mptx2, Olfr1404, Olfr418, Ackr1, Cadm3, Aim2 | |
| 1: 174455423 | 4.22E−06 | rs31561177 | 0.4 | Igfs8, Atp1a2, Kcnj9, Kcnj10, Pigm, Igsf9, Slamf9, Tafln2, Cfap45, Slamf8, Fcrl6, Dusp23, Crp | |
| 7: 87409991 | 4.61E−06 | rs4226715 | 0.2 | ###Rik, Zfp710, idh2, Cib1, Ttll13, Ngrn, Rccd1, Prc1, Unc45a, Vps33b, Man2a2, Fes, Furin, Blm | |
| 1: 174239958 | 4.98E−06 | rs30472229 | 0.25 | Ncstn, Copa, Pex19, Dcaf8, Pea15a, Casaq1, Igfs8, Atp1a2, Kcnj9, Kcnj10, Pigm, Igsf9, Slamf9 | |
| GST day 6 | 4: 138646868 | 2.29E−07 | rs32914632 | 0.2 | Otud3, Pla2g2a, Pla2g2e, Rnf186, Tmco4, Htr6, Nbl1, Minos, Capzb, Pqlc2 |
| 4: 138129729 | 5.93E−07 | rs32007081 | 0.25 | Cda, Fam43b, Mul1, ABO41806, Camk2n1, Vwa5b1, Ubxn10, Pla2g2c, Pla2g25 | |
| 4: 137042287 | 6.80E−07 | rs27577055 | 0.25 | Wnt4, Cdc42, Cela3a, Cela 3b, Hspg2, Ldlrad2, ####Rik, Usp48, Rap1gap | |
| 4: 137353761 | 9.71E−07 | rs8256572 | 0.33 | Ldlrad2, ####Rik, Usp48, Rap1gap, Rap1gapcs, Alpl, Ece1, Eif4g3 | |
| 4: 138291047 | 1.13E−06 | rs27575102 | 0.4 | ABO41806, Camk2n1, Vwa5b1, Ubxn10, Pla2g2c, pla2g25, Otud3, Pla2g2a | |
| GST retest | 4: 150729074 | 6.53E−07 | rs32163108 | 0.4 | Camta1 |
| 4: 150886138 | 7.71E−07 | rs32757832 | 0.25 | Camta1 | |
| 4: 150659779 | 1.11E−06 | rs13478053 | 0.5 | Vamp3, Camta1 | |
| 4: 150681054 | 1.97E−06 | rs32590839 | 0.667 | Uts2, Per3, Vamp3, Camta1 | |
| 4: 150745317 | 2.26E−06 | rs32180816 | 0.5 | Camta1 |
a
Position relative to NCBI Build 37 genome assembly.
b
Minor allele frequency.
c
Genes in bold are considered the best candidates for influence over trait.