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. 2017 Jun 17;7(8):2651–2664. doi: 10.1534/g3.117.043836

Figure 4.

Figure 4

Mean ± SEM of the ratio of low cSOD: high cSOD activity longevities for adult male and female flies across the eight DGRPi genetic backgrounds. Values closer to 1 indicate more similar longevities at the levels of cSOD activity being compared, and C.I.s are at 95% and represent the ratio of the low cSOD activity and high cSOD activity SEMs. (A) 0% cSOD activity: 50% cSOD activity: Female: lowest ratio 304, 0.0846 < 0.0972 < 0.111; highest ratio 820, 0.162 < 0.180 < 0.201; Male: lowest ratio 335, 0.0715 < 0.0793 < 0.0873, highest ratio 313, 0.143 < 0.165 < 0.188 (B) 30% cSOD activity: 80% cSOD activity: Female: lowest ratio 304, 0.535 < 0.650 < 0.780; highest ratio 307, 0.889 < 0.990 < 1.10; Male: lowest ratio 324, 0.642 < 0.720 < 0.803; highest ratio 820, 1.05 < 1.21 < 1.42. ANOVA was used to test the factor effects with an α of 0.05. Partial eta squared (ηp2) was calculated to quantify the effect of each factor. (A) Sex-by-genetic background-by-cSOD activity, F7,2227 = 4.38, P < 0.0001, ηp2 = 0.0136. (B) Sex-by-genetic background, F7,1673 = 2.91, P = 0.0049, ηp2 = 0.0121; genetic background-by-cSOD activity; F7,1673 = 6.03, P < 0.0001, ηp2 = 0.0246. cSOD, cytosolic copper/zinc superoxide dismutase.