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. 2017 Jun 17;7(8):2651–2664. doi: 10.1534/g3.117.043836

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Copyright © 2017 Lessel et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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(A and B) Mean ± SEM of MEN activity; (C and D) mean ± SEM of the IDH activity; and (E and F) mean ± SEM of G6PD activity, standardized by protein concentration (micrograms per milliliter) for adult male and female flies pooled across the eight DGRPi genetic backgrounds within each 3rd chromosome genotype. ANOVA was used to test the factor effects with an α of 0.05. Partial eta squared (η_p²) was calculated to quantify the effect of each factor. (A) Sex-by-cSOD activity, F_1,265 = 31.8, P < 0.0001, η_p² = 0.110. (B) Sex-by-cSOD activity, F_1,280 = 10.5, P = 0.0013, η_p² = 0.0363. (C) Sex-by-cSOD activity, F_1,265 = 25.5, P < 0.0001, η_p² = 0.0879. (D) Sex, F_1,280 = 4.58, P = 0.0333, η_p² = 0.0161. (E) Sex-by-cSOD activity, F_1,265 = 19.6, P < 0.0001, η_p² = 0.0690. (F) Sex, F_1,280 = 155.2, P < 0.0001, η_p² = 0.357. Brackets enclose significantly different groups. cSOD, cytosolic copper/zinc superoxide dismutase; DGRPi, ; G6PD, glucose-6-phosphate dehydrogenase; IDH, isocitrate dehydrogenase; MEN, malic enzyme.