Table 1. Variants detected by whole-genome resequencing of one affected Malinois puppy (MA163).
| Filtering Step | Number of Variants |
|---|---|
| Variants in the whole genomea | 1,889,727 |
| Variants in the critical 10.6 Mb interval on chromosome 5 | 75,231 |
| Variants in the critical interval that were absent from 146 other dog genomes | 37 |
| Protein-changing variants in the whole genomea | 7936 |
| Protein-changing variants in the 10.6 Mb critical interval on chromosome 5 | 817 |
| Protein-changing variants in the critical interval, absent from 146 other dog genomes | 0 |
a
The sequences were compared to the reference genome (CanFam 3.1) from a Boxer. Protein-changing variants were classified based on the ENSEMBL annotation (version 72).