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. 2017 Aug 14;12(8):e0183187. doi: 10.1371/journal.pone.0183187

Fig 1. Schematic of GDF15 mRNA harboring putative miR-873-5p/miR-1233-3p binding sites and SNP rs1054564 G>C in the 3′ UTR.

Fig 1

Alignment shows the GDF15 3′ UTR variant rs1054564 G>C region with the miRNA hsa-miR-873-5p and hsa-miR-1233-3p motifs. The location of the rs1054564 G>C polymorphism is designated with an arrow in the sequence alignment. Allele G forms a Watson-Crick base-pair with C in the miRNAs (solid line), whereas allele C does not (no line). The seed regions of both miRNAs are designated with an open box. The dots between the base pairs G:U represent GU wobble pairs.