Fig 2. In silico analysis of the pairing of miR-873-5p and miR-1233-3p to the binding site in the 3′ UTR of GDF15 showing the effect of the minor allele of rs1054564 on the hybrid structures formed between hsa-miR-873-5p/hsa-miR-1233-3p and the GDF15 3′ UTR.

Allele C disrupts the stem part of the typical stem-loop RNA folding structure. The arrow indicates the SNP site in the GDF15 3′ UTR in each folding structure.