Fig 4. Effect of hsa-miR-873-5p and hsa-miR-1233-3p mimic miRNAs on GDF15 protein expression in human melanoma A2058 cells.

Endogenous GDF15 was suppressed by both mimic miRNAs and restored by miRNA inhibitors. Data represent expression levels relative to those of control samples and indicate the mean of three independent experiments; error bars indicate SE. p-values were determined by a Student’s t-test, and * denotes a p-value < 0.05.