Table 1. Prediction results of miRNAs targeting the GDF15 3′ UTR SNP rs1054564.
Gene | SNP | Allele | miRNA | Conserveda | mirSVRb | Energyc | Scored | Seed region |
---|---|---|---|---|---|---|---|---|
GDF15 | rs1054564 | G | hsa-miR-873-5p | yes | -0.1265 | -28.4 | 97 | no |
C | -26.0 | |||||||
G | hsa-miR-1233-3p | no | -0.0096 | -27.1 | 89 | yes | ||
C | -21.4 |
aConservation information among vertebrates from microRNA.org
bmirSVR score of binding site from microRNA.org
cFree energy of miRNA–mRNA duplex from RNAhybird
dPredicted score of miRNA–mRNA binding by TargetScan. The higher the score the more stable the binding.