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. Author manuscript; available in PMC: 2017 Aug 14.
Published in final edited form as: Nat Struct Mol Biol. 2017 Jan 23;24(3):214–220. doi: 10.1038/nsmb.3364

Figure 4.

Figure 4

Interaction of Nmd3 RBDII with 25S rRNA. (a) Overview of the interaction between RBDII and 25S rRNA. The orientation is represented in the illustration on the lower left. (b) The α1 helix of RBDII interacts with H68. (c) R303 from the α2 helix of RBDII stacks with G2418 of H74 and U2965 of H93. (d) Conformational difference between G2418 in the pre-60S map and in its mature state. Coordinates of the mature state (tan) are from the crystal structure of the yeast 80S ribosome (PDB 3U5E)27. (e) Interactions of the β-strand elements of RBDII with the junction of H68–H69.