Figure 3.

Activation of RARE and p53 gene by E/P and retinoids in 76N TERT cells. Cells were transiently transfected with the RARE (A) or p53 (B) reporter plasmid, and then treated with retinoids for 24 hours with or without E/P. Luciferase activity was measured and normalized as described under "Materials and Methods". Results are the means ± SE from 3 experiments. *, significant differences from control.