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. Author manuscript; available in PMC: 2017 Aug 14.
Published in final edited form as: Biochemistry. 2016 Mar 16;55(12):1749–1757. doi: 10.1021/acs.biochem.6b00026

Scheme 1.

Scheme 1

A Homologous Targeting Strategy for PNA Hybridization to G-Quadruplex DNAa

aA short, homologous PNA can invade a DNA G-quadruplex forming a 2PNA:1DNA heteroquadruplex.