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. Author manuscript; available in PMC: 2017 Aug 14.
Published in final edited form as: Biochemistry. 2016 Mar 16;55(12):1749–1757. doi: 10.1021/acs.biochem.6b00026

Table 3.

PNA-DNA Heteroquadruplex Melting Temperature (Tm, °C) and Stabilization Relative to DNA Homoquadruplex (ΔTm, °C) Determined in 100 mM K+a

DNA Tm ΔTm
QFS3 61.6 ± 0.4 6.7
QFS3L2 75.6 ± 3.1 18.9
QFS3L3 77.2 ± 3.9 8.5
hTERTb >95 >30
a

[DNA] = 1 µM, [Peg2] = 2 µM.

b

Measured in 10 mM K+.