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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: J Immunol. 2016 Sep 28;197(9):3650–3661. doi: 10.4049/jimmunol.1600820

Figure 7. CCR7-deficient mice are protected from HFD-induced insulin resistance and adipose tissue inflammation.

Figure 7

(A) Body weights of WT and Ccr7−/− mice during 8 weeks HFD feeding. (B) Organ weights at the end of HFD exposure. (C) Fasting blood glucose and plasma insulin levels. (D) HOMA-IR in WT and Ccr7−/−mice fed and HFD for 8 weeks. (E) Immunofluorescence imaging of Mac2+ ATM (red) and caveolin+ adipocytes (green) in eWAT. Scale bar = 100μm. (F) Expression of inflammatory genes in eWAT from HFD-fed WT and Ccr7−/− mice. *, p<0.05; **,p<0.01; #=0.06.