Head-tracking to high contrast square-wave gratings. (A)
Photograph of head-tracking apparatus showing RCS rat in holding
chamber and rotating drum lined with square-wave grating.
(B) Total amount of time h1RPE7-grafted animals spent
tracking a moving square-wave grating in seconds over a period of 4 min
after 10 weeks posttransplant. (C) Head-tracking 20
weeks after h1RPE7 transplantation. Error bars represent SEM. *,
P < 0.05, represents statistical difference in
nondystrophic h1RPE7-grafted animals as compared to sham and dystrophic
groups. (D) Comparative analysis of mean tracking over
all frequencies for ARPE19, h1RPE7, and sham showed a significant
difference (F = 7.05; df = 2, 23;
P < 0.01 Student–Neuman–Keuls post hoc analysis)
between sham and both transplant groups but no significant difference
between transplant groups.