Table 1. Hemodynamic values in perfused hearts from controls, mice with IGF-1 deficiency (Hz) and Hz treated with IGF-1 therapy.

Results before ischemia
Experimental group	Heart rate (beats/min)	Coronary perfusion pressure (mmHg)	Left IV developed pressure (mmHg)	dP/dt (mmHg/s)
Controls (Wt) (Igf+/+)	315 ± 31	59 ± 10	47 ± 7	1748 ± 315
Untreated IGF-1 deficient mice. (Hz) (Igf+/-)	298 ± 11	63 ± 15	31 ± 7	1256 ± 270
Deficient mice treated with IGF-1 (Hz + IGF-1)	285 ± 31	49 ± 8	36 ± 6	1465 ± 259
Results after ischemia-reperfusion
Experimental group	Heart rate (beats/min)	Coronary perfusion pressure (mmHg)	Left IV developed pressure (mmHg)	dP/dt (mmHg/s)
Controls (Wt) (Igf+/+)	188 ± 17	41 ± 6	25 ± 8	644 ± 239
Untreated IGF-1 deficient mice. (Hz) (Igf+/-)	264 ± 37 #	35 ± 4	32 ± 10	1140 ± 363#
Deficient mice treated with IGF-1 (Hz + IGF-1)	160 ± 42 &	49 ± 9	26 ± 6	818 ± 259&

n = 5 animals per group.

# p<0.05 Hz vs. control group

& p<0.05 Hz+IGF-1 vs. untreated Hz group.