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. 2017 Jun 30;6:e26575. doi: 10.7554/eLife.26575

Table 2.

Self-renewal (Mouse)

DOI: http://dx.doi.org/10.7554/eLife.26575.037

Reagent Company Cat no Final concentration
Advanced DMEM ThermoFisher Scientific, Invitrogen 12634–010 n/a
Penicillin/Streptomycin ThermoFisher Scientific, Invitrogen 15140–122 100 U/ml (Pen)
100 μg/ml (Strep)
Hepes ThermoFisher Scientific, Invitrogen 15630–056 10 mM
Glutamax ThermoFisher Scientific, Invitrogen 35050–038 2 mM
N2 ThermoFisher Scientific, Invitrogen 17502–048 1:100
B27 (-Vit A) ThermoFisher Scientific, Invitrogen 12587–010 1:50
N-acetylcysteine Sigma-Aldrich A9165 1.25 mM
Matrigel Corning 356231 Undiluted
R-spondin conditioned medium Stem Cell Institute, University of Cambridge From 293T-HA-Rspo1-Fc cell line made by Calvin Kuo, Stanford 5% v/v
mEGF R and D Systems 2028-EG-200 50 ng/ml
Noggin R and D Systems 6057 NG-100 100 ng/ml
FGF10 R and D Systems 345-FG-025 100 ng/ml
mFGF7 R and D Systems 5028 KG_025 100 ng/ml
CHIR 99021 Stem Cell Institute, University of Cambridge n/a 3 μM
SB 431542 Tocris 1614 10 μM