Skip to main content
. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Shock. 2017 Sep;48(3):346–354. doi: 10.1097/SHK.0000000000000855

Figure 4. CDNPs are ingested by neutrophils, inflammatory monocytes and macrophages at the infection site.

Figure 4

Mice were treated with 5µg CFSE-labeled CDNPs at the time of CLP induction and peritoneal cells were analyzed 4h later. Pooled data from 2 independent experiments with n =8-9 mice per group. A) Association of CDNPs with peritoneal cells was determined by CFSE fluorescence. B) Ingestion of CDNPs was assessed after surface fluorescence quenching with trypan blue. C) Percentages of CFSE positive cells within distinct peritoneal cell subsets. D) MFI of CFSE within distinct peritoneal cell subsets (D). A and B show representative FACS plots gated on all cells. Data in C and D are expressed as means ± SEM. Significance was determined using Student's t-test. **p<0.01, ***p<0.001.