. Author manuscript; available in PMC: 2018 Sep 1.

Published in final edited form as: Pediatr Infect Dis J. 2017 Sep;36(9):855–859. doi: 10.1097/INF.0000000000001610

Table 1.

Laboratory Adverse Events and Serious Adverse Events.

	Adverse Events		Serious Adverse Events
Laboratory Event	AE Values	Infants n=746 (%)	SAE Values	Infants n=746 (%)
Hypernatremia	>155 mmol/L	18 (2)	>160 mmol/L	1 (0.1)
Hypokalemia	<3 mmol/L	43 (6)	<2.5 mmol/L	10 (1)
Elevated creatinine	>1.7 mg/dL	14 (2)	>3.0 mg/dL	0 (0)
Leukopenia	<5000/mm³	93 (12)	<2000/mm³	7 (1)
Thrombocytopenia	<100,000/mm³	242 (32)	<30,000/mm³	70 (9)
Low hematocrit	<37%	263 (35)	<30%	60 (8)
Prolonged prothrombin time	>15 sec	16 (2)	-	-
Prolonged partial thromboplastin time	>50 sec	9 (1)	-	-
High AST	>600 U/L	7 (1)	>1200 U/L	2 (0.3)
High ALT	>225 U/L	4 (0.5)	>450 U/L	2 (0.3)

Abbreviations: AST, aspartate aminotransferase; ALT, alanine transaminase