. Author manuscript; available in PMC: 2018 Sep 1.

Published in final edited form as: J Bone Miner Res. 2017 Jun 12;32(9):1900–1906. doi: 10.1002/jbmr.3168

Table 4. BMI (Quartiles) and Risk for Incident Primary Hyperparathyroidism.

	Body Mass Index
	Q1	Q2	Q3	Q4	P-trend

Range (kg/m²)	≤22.0	22.1-24.1	24.2-27.4	≥27.5
Median BMI (kg/m²)^a	20.8	23.0	25.6	30.3
Incident Cases of P-HPTH	109	104	128	146
Person-years of Follow-Up	511,979	511,723	511,404	511,063
Age-adjusted RR	Ref	0.94 (0.71, 1.22)	1.14 (0.88, 1.47)	1.27 (0.99, 1.63)	0.02
Multivariate-adjusted Model 1 RR^*	Ref	0.92 (0.70, 1.20)	1.09 (0.84, 1.42)	1.16 (0.89, 1.53)	0.14
Multivariate-adjusted Model 2 RR^**	Ref	0.93 (0.71, 1.22)	1.13 (0.86, 1.49)	1.25 (0.93, 1.70)	0.07

Data from baseline in 1986

Model 1: Multivariable model includes age, race, smoking status (past, current, never), physical activity (quintiles), menopausal status (pre or post), postmenopausal hormone use (yes or no), physical examination in prior two years, bisphosphonate use, history of hypertension, diabetes, chronic kidney disease, congestive heart failure, or osteoporosis, total vitamin D and vitamin A intake, supplemental calcium and alcohol intake, dietary intakes of calcium, magnesium, and protein, and UV-B radiation flux.

^**

Model 2: Multivariable model includes adjustment for all variables in Model 1 and also predicted 25(OH)D levels

Note: BMI values for the year 2000 are shown; however BMI was updated over the course of the study.