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. 2017 May 7;83(9):2077–2086. doi: 10.1111/bcp.13295

Table 3.

Sensitivity analyses

No. with pneumonia No. quasi‐cohort (person‐days) Quasi‐rates per 1000 person‐years Rate ratio
Crude Adjusteda (95% CI)
Sensitivity analysis 1: excluding outcomes of hospitalization with pneumonia as secondary diagnosis
Non‐users b 933 10 872 1.41 1.00 Ref
Current users 268 1133 3.88 2.76 1.91 (1.56, 2.33)
Sensitivity analysis 2: excluding last 15 days prior to index person‐moment
Non‐users b 1662 18 190 2.41 1.71 Ref
Current users 266 1085 6.46 2.68 1.48 (1.22, 2.78)
Sensitivity analysis 3: classifying non‐users into past users and never users
Never users c 1201 14 676 2.15 1.00 Ref
Past users 314 2766 2.99 1.39 1.12 (0.96, 1.30)
Current users 413 1833 5.93 2.75 1.88 (1.60, 2.20)
Sensitivity analysis 4: stratifying non‐ICS users into current and non‐current users of other respiratory medications
Non‐ICS users currently using other respiratory medications
Current users 413 1833 3.69 1.82 1.61 (1.38, 1.89)
Non‐users b 1257 10 157 2.03 Ref Ref
Non‐ICS users not currently using other respiratory medications
Current users 413 1833 2.81 6.36 4.81 (3.56, 6.51)
Non‐users b 258 7285 0.44 Ref Ref
Sensitivity analysis 5: stratifying non‐ICS users and excluding last 15 days prior to index‐person moment
Non‐ICS users currently using other respiratory medications
Current users 214 969 3.62 1.67 1.32 (1.09, 1.60)
Non‐users b 1456 11 021 2.16 Ref Ref
Non‐ICS users not currently using other respiratory medications
Current users 214 969 2.49 6.24 3.07 (2.08, 4.51)
Non‐users b 258 7285 0.40 Ref Ref
Sensitivity analysis 6: restricting asthma patients to those with three prescriptions on at least two occasions over the span of 1 year
Current users 189 946 4.58 2.47 1.74 (1.37, 2.21)
Non‐users b 389 4801 1.86 Ref Ref

CI, confidence interval

a

Adjusted for all of the factors listed in Table 1 unless otherwise indicated.

b

Reference group (Ref); refers to no use of ICS (fluticasone, budesonide, beclomethasone, flunisolide or triamcinolone) in the 60 days prior to the index person‐moment.

c

Reference group; refers to no use of ICS (fluticasone, budesonide, beclomethasone, flunisolide or triamcinolone) in the 365 days prior to the index person‐moment.