Table 3.

Cox proportional hazards for the cardiac outcomes in the MI population in a fully adjusted model, n = 1585

	Death	Myocardial infarction	Acute coronary syndrome
Outcomes:	n = 199	n = 40	n = 98
Risk factors	HR (95%CI)	HR (95%CI)	HR (95%CI)
Age at index date (per year)	1.05 (1.03–1.06)	1.02 (0.99–1.04)	1.01 (0.99–1.03)
Female	0.80 (0.58–1.11)	0.83 (0.40–1.71)	0.72 (0.44–1.16)
Year of trigger event	1.04 (0.95–1.14)	1.02 (0.84–1.24)	1.07 (0.95–1.21)
Diabetes	1.53 (1.13–2.08)	1.69 (0.85–3.39)	1.65 (1.05–2.59)
ACS prior to trigger event	1.40 (1.00–1.97)	1.12 (0.52–2.40)	1.33 (0.84–2.12)
Stroke	0.94 (0.51–1.72)	/	0.53 (0.13–2.18)
Atrial fibrillation	1.49 (1.06–2.10)	1.65 (0.69–3.92)	0.86 (0.45–1.64)
Heart failure	1.56 (1.14–2.14)	1.09 (0.50–2.33)	1.33 (0.82–2.17)
Renal disease	1.59 (1.05–2.39)	1.09 (0.30–3.90)	0.86 (0.36–2.09)
Hypertension	1.09 (0.78–1.53)	0.74 (0.37–1.50)	0.87 (0.56–1.37)
Hospitalized bleeding	1.02 (0.65–1.58)	0.52 (0.12–2.30)	0.75 (0.34–1.67)
COPD	1.58 (1.08–2.31)	1.93 (0.78–4.74)	2.33 (1.34–4.07)
Cancer	2.01 (1.43–2.83)	0.14 (0.02–1.06)	0.64 (0.32–1.31)
PAD	1.75 (1.18–2.61)	2.13 (0.89–5.11)	1.25 (0.66–2.38)

HR: hazard ratio; CI: confidence interval.

MI: myocardial infarction; ACS: MI or unstable angina; HR: hazards ratio; COPD: chronic obstructive pulmonary disease; PAD: peripheral arterial disease.

Exposure to medication cited in Table 1 is included in the adjustment model.

In bold: hazard ratios whose lower 95% confidence interval does not overlap 1.