FIGURE 4.
Baicalein abolished tumorigenesis of pNETs in mice. A, BON1 xenograft tumors from the treatment experiment. Mice were killed 7 weeks after baicalein treatment. B, The tumor volumes were calculated according to the following formula: volume = length × width2 / 2. C, The protein obtained from primary tumors in mice with or without baicalein treatment. The levels of Bax, Bcl-2, VEGF, survivin, MMP-2, and MMP-9 were analyzed by Western blot, and quantification assay of Western blot results is also presented. *P < 0.05, **P < 0.01, ***P < 0.001.