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. 2017 Aug 14;7:8024. doi: 10.1038/s41598-017-08603-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Analysis of mRNA and lncRNA expression data in control, IBM and Jo-1 myositis. (a) Venn diagram showing overlap between differentially expressed mRNAs in IBM and Jo-1 myositis, (b) Changes in levels of β₂-microglobulin (B2M), CD74 and IGF2 mRNA expression were confirmed by qRT-PCR. The data are presented as the mean ± SEM of 4–5 patients where *p < 0.05 and ***p < 0.001 (Mann-Whitney U-test). (c) Pathway analysis of differentially expressed mRNAs in IBM and Jo-1 myositis, (d) Classification of Gencode and novel lncRNA in skeletal muscle and, (e) List of most highly expressed lncRNA in control skeletal muscle.