Table 2.
Strategy | Experimental result | Theoretical category* |
---|---|---|
Increasing drug concentration | Observed | CT |
CIAP inhibition | Observed | CT |
BCL inhibition | Observed | BG |
Nutlin | Observed | CT |
Inhibition of both CIAP and BCL | Prediction | AB |
Caspase8 activation | Prediction | BG |
*Three categories:
1. BG- alteration of bifurcation geometry;
2. CT- alteration of cellular trajectory;
3. AB- alteration of both bifurcation geometry and cellular trajectory.