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. 2017 Aug 14;7:8066. doi: 10.1038/s41598-017-08559-w

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Liver weight, triglyceride content and gene expression of lipid metabolism markers in the maternal and fetal liver. (A) Weight of dams liver (CD-Veh, n = 8; HF/HS, n = 8; CD-DHT, n = 8; HF/HS-DHT, n = 10). (B) Circulating Triglycerides (TG) in serum and (C) TG content in dams liver, (CD-Veh, n = 8; HF/HS-Veh, n = 8; CD-DHT, n = 8; HF/HS-DHT, n = 9). (D) TG content in fetal liver (CD-Veh, n = 7; HF/HS, n = 8; CD-DHT, n = 8; HF/HS-DHT, n = 9). (E) Correlation analyses between TG content in fetal liver and maternal weight gain before pregnancy, (F) Correlation analyses between TG content in fetal liver and percentage of maternal weight gain during pregnancy, (G) Correlation analyses between TG content in maternal liver and percentage of maternal weight gain before pregnancy, (H) Correlation analyses between TG content in maternal liver and percentage of maternal weight gain during pregnancy, (I) Transcription factors, lipogenic enzymes, cholesterol and fat storage mediators in Maternal liver and (J) fetal liver (CD, n = 8; HF/HS, n = 8; CD-DHT, n = 7–8; HF/HS-DHT, n = 10). Values are means ± SEM. a = Main effect of diet, b = main effect of injection, 1 = Interaction between diet and injection.