Table 5.
HRs for POF, PNec and in-hospital mortality by quartiles of lipid profiles using multivariable analysis.
| 1st Quartile | 2nd Quartile | 3rd Quartile | 4th Quartile | P-value for trend | |
|---|---|---|---|---|---|
| POF | |||||
| TG | 1.00 (reference) | 1.61 (0.86, 3.00) | 0.95 (0.46, 1.97) | 1.99 (0.80, 4.99) | 0.352 |
| T-CHO | 1.00 (reference) | 0.83 (0.45, 1.51) | 0.54 (0.29, 1.01) | 0.74 (0.38, 1.47) | 0.169 |
| HDL-C | 1.00 (reference) | 0.53 (0.31, 0.92) | 0.23 (0.12, 0.43) | 0.20 (0.10, 0.39) | <0.001 |
| LDL-C | 1.00 (reference)1 | 0.77 (0.45, 1.34) | 0.83 (0.45, 1.53) | 0.66 (0.36, 1.20) | 0.207 |
| TG/HDL-C | 1.00 (reference) | 1.67 (0.84, 3.33) | 2.02 (0.99, 4.13) | 3.68 (1.53, 8.84) | 0.005 |
| Non-HDL-C | 1.00 (reference) | 0.72 (0.39, 1.33) | 0.96 (0.52, 1.76) | 0.87 (0.43, 1.77) | 0858 |
| PNec | |||||
| TG | 1.00 (reference) | 1.83 (1.10, 3.04) | 0.75 (0.42, 1.36) | 1.95 (0.97, 3.88) | 0.314 |
| T-CHO | 1.00 (reference) | 1.07 (0.64, 1.77) | 0.98 (0.60, 1.61) | 1.07 (0.61, 1.89) | 0.911 |
| HDL-C | 1.00 (reference) | 0.64 (0.41, 0.99) | 0.27 (0.17, 0.45) | 0.43 (0.26, 0.71) | <0.001 |
| LDL-C | 1.00 (reference) | 0.88 (0.56, 1.37) | 0.96 (0.59, 1.56) | 0.69 (0.42, 1.12) | 0.183 |
| TG/HDL-C | 1.00 (reference) | 1.53 (0.89, 2.61) | 0.98 (0.55, 1.75) | 2.06 (1.06, 4.02) | 0.111 |
| Non-HDL-C | 1.00 (reference) | 0.76 (0.45, 1.27) | 1.28 (0.78, 2.09) | 1.04 (0.59, 1.83) | 0.474 |
| In-hospital mortality | |||||
| TG | 1.00 (reference) | 2.13 (0.90, 5.05) | 1.04 (0.33, 3.23) | 0.75 (0.17, 3.36) | 0.861 |
| T-CHO | 1.00 (reference) | 0.39 (0.15, 0.97) | 0.23 (0.07, 0.70) | 0.42 (0.15, 1.14) | 0.017 |
| HDL-C | 1.00 (reference) | 0.79 (0.34, 1.83) | 0.50 (0.19, 1.32) | 0.42 (0.15, 1.18) | 0.043 |
| LDL-C | 1.00 (reference) | 0.91 (0.42, 1.96) | 0.82 (0.30, 2.23) | 0.70 (0.27, 1.82) | 0.457 |
| TG/HDL-C | 1.00 (reference) | 1.78 (0.67, 4.73) | 1.67 (0.57, 4.89) | 0.71 (0.17, 2.90) | 0.942 |
| Non-HDL-C | 1.00 (reference) | 0.54 (0.23, 1.26) | 0.50 (0.20, 1.26) | 0.30 (0.10, 0.91) | 0.027 |
*Multivariate analysis: adjustment for sex, age, biliary etiology, smoking habit, alcohol intake, diabetes mellitus, obesity, history of pre-existing organ dysfunctions including history of chronic pulmonary disease, chronic renal disease and cardiovascular disease, admission laboratory data including total leukocyte count, serum glucose, and calcium.
HDL-C quartiles: quartile 1, <0.81 mmol/L; quartile 2, 0.81–1.06 mmol/L; quartile 3, 1.07–1.34 mmol/L; quartile 4, ≥1.35 mmol/L; LDL-C quartiles: quartile 1, <1.26 mmol/L; quartile 2, 1.26–1.84 mmol/L; quartile 3, 1.85–2.36 mmol/L; quartile 4, ≥2.37 mmol/L; Non-HDL-C quartiles: quartile 1, <2.29 mmol/L; quartile 2, 2.29–3.01 mmol/L; quartile 3, 3.02–4.40 mmol/L; quartile 4, ≥4.41 mmol/L; TG quartiles: quartile 1, <0.87 mmol/L; quartile 2, 0.87–1.51 mmol/L; quartile 3, 1.52–4.29 mmol/L; quartile 4, ≥4.30 mmol/L; T-CHO quartiles: quartile 1, <3.36 mmol/L; quartile 2, 3.36–4.12 mmol/L; quartile 3, 4.13–5.45 mmol/L; quartile 4, ≥5.46 mmol/L; TG/HDL-C quartiles: quartile 1, <0.76; quartile 2, 0.76–1.52; quartile 3, 1.52–6.65; quartile 4, ≥6.66.
Abbreviations: CI: confident interval; HDL-C, high-density lipoprotein cholesterol; HR, hazard ratio; LDL-C, low-density lipoprotein cholesterol; PNec, pancreatic necrosis; POF, persistent organ failure; T-CHO, total cholesterol; TG, triglycerides.