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. 2017 Aug 14;7:8114. doi: 10.1038/s41598-017-08838-6

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Axial MR images used to identify and characterize PDAC tumours in the mouse abdomen. Tumour is outlined. (A) T2-weighted image. T = tumour, N = necrosis, Sp = spleen, K = kidney, Int = intestine. (B) Pre-injection inversion recovery image (TR/TE/TI = 3200 ms/9.6 ms/487 ms). (C) Pre-injection T1-weighted image shows little contrast between tumour and surrounding tissue. (D) T1-weighted image at 5 min after injection of the collagen-targeted probe shows improved contrast and heterogeneous signal enhancement within the tumour.