Table 2.
General physicochemical properties of antibiotic substrates of AcrB and AcrD.
| Antibiotic substrate type (Physicochemical property) | E. coli | |
|---|---|---|
| AcrB | AcrD | |
| Hydrophobic | + | − |
| Hydrophilic | − | + |
| Amphiphilic | + | + |
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