Table 1.
Time post PHx | Wildtype (C57Bl/6) | DeltaKlf6 | ||||
---|---|---|---|---|---|---|
12 h | 24 h | 72 h | 12 h | 24 h | 72 h | |
ALT [U/l] | 899.0 ± 649.2 | 315.8 ± 65.9 | 20.4 ± 4.4 | 2015.3 ± 357.1 | 395.0 ± 244.1 | 14.0 ± 3.6 |
AST [U/l] | 2093.0 ± 513.3 | 753.0 ± 98.6 | 94.2 ± 2.04 | 3321.0 ± 645.6 | 462.5 ± 98.6 | 73.0 ± 10.0 |
Total bilirubin [mg/dl] | 0.37 ± 0.12 | 0.45 ± 0.15 | 0.3 ± 0.0 | 0.23 ± 0.042 | 0.3 ± 0.0 | 0.23 ± 0.07 |
Liver/bodyweight ratio [%] | 1.8 ± 0.09 | 1.75 ± 0.31 | 2.5 ± 0.19 | 2.28 ± 0.009** | 2.5 ± 0.23** | 2.1 ± 0.18 |
**p < 0.01 (wt vs. DeltaKlf6 at same time-point).