Table 3. Different characteristics of micro- and macrovascular stroke.

Stroke types	Microvascular	Macrovascular
Designations	Lacunar infarction Hemorrhagic stroke (including microbleeds)	Cortical infarction
Main causes	Lipohyalinosis	Atherosclerosis Thromboembolism
Vascular territories	Small deep perforating arteries	Cerebral/carotid/vertebral arteries
Association with aortic stiffness	+	+
Suggested central hemodynamic mechanisms	High aortic pressure	High aortic pressure Aortic flow reversal