Table 1.
Benefits (deaths, life years, and quality adjusted life years (QALYs)) and costs of nurse led secondary prevention clinics for coronary heart disease compared with control group
| Variable | Intervention group (n=673) | Control group (n=670) | Difference (95% CI) | P value | Comment |
|---|---|---|---|---|---|
| No of deaths | 100 | 128 | 28 | 0.038 | |
| Mean life years* | 4.590 | 4.483 | 0.110 (0.012 to 0.210) | 0.028 | As observed over mean 4.7 years follow up |
| Mean QALYs at end of follow up | 3.175 | 3.051 | 0.124 (0.059 to 0.189) | <0.001 | Area under curve |
| Costs of intervention (£)* | 1015 | 879 | 136 (56 to 216) | <0.001 | t test |
| Other NHS costs (£) per patient | 2005 | 2238 | −233 (−766 to 299) | 0.390 | t test |
| Incremental cost per life year (£) | — | — | 1236 (268 to 17 983) | Not applicable | Box method15 |
| Incremental cost per QALY (£) | — | — | 1097 (298 to 3633) | Not applicable | Box method15 |
| Incremental net benefit (£) | — | — | 3584 (3501 to 3667) | <0.001 | Using threshold of £30 000/QALY |
Benefits discounted at 3.5% and costs discounted at 3.5%. Intervention includes costs for clinic and increased prescribing per patient.
*
Discounted over four years at 3.5%.