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.gov website belongs to an official
government organization in the United States.
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A lock (
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DUF1220 domains cluster by sequence similarity into six major clades. A Neighbor-Joining tree of DUF1220 domain protein sequences was constructed with Geneious v. 10.0.5. Branch colors represent the clade that each DUF1220 domain has been assigned to. DUF1220 domains for which the sequence is a hybrid of two major clades are in black. The aligned sequence data supporting the clade assignments can be found in Additional file 6
