TABLE 1.
Orlistat (Xenical, Alli*) | Lorcaserin (Belviq) | Phentermine/Topiramate (Qsymia) | Naltrexone/ Bupropion (Contrave) | Liraglutide (Saxenda) | |
---|---|---|---|---|---|
Weight loss (%) | |||||
Drug | 6.2 | 4.5 | 9.6 | 5.0 | 6.0 |
Placebo | 4.3 | 1.5 | 2.6 | 1.8 | 2.0 |
A1C change (%) | |||||
Drug | −0.3 | −0.9 | −1.6 | −0.6 | −1.3 |
Placebo | +0.2 | −0.4 | −1.2 | −0.1 | −0.3 |
Brand names are in parentheses; study lengths were 52–56 weeks. *Over-the-counter brand name. |