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. 2017 Aug;30(3):149–153. doi: 10.2337/ds17-0011

TABLE 1.

Weight Loss Medications in People With Type 2 Diabetes: Weight Loss and Glucose Outcomes (19)

Orlistat (Xenical, Alli*) Lorcaserin (Belviq) Phentermine/Topiramate (Qsymia) Naltrexone/ Bupropion (Contrave) Liraglutide (Saxenda)
Weight loss (%)
 Drug 6.2 4.5 9.6 5.0 6.0
 Placebo 4.3 1.5 2.6 1.8 2.0
A1C change (%)
 Drug −0.3 −0.9 −1.6 −0.6 −1.3
 Placebo +0.2 −0.4 −1.2 −0.1 −0.3
Brand names are in parentheses; study lengths were 52–56 weeks. *Over-the-counter brand name.