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Consolidated standards of reporting trials (CONSOT) flowchart. HTN hypertension, Metfm metformin, ACA ascorbic acid (vitamin C), ASA acetylsalicylic acid (aspirin), OD once daily, Blinded single blinding = participant doesn’t know about the drug active ingredient, D/DM duration of diabetes mellitus, BMI body mass index, PA physical activity, ES/NS ever smoke/never smoke, D/C discontinue
