Table 1.

Characteristics of patients with rectal cancer with or without local recurrence following surgery

	Local Recurrence (n, %)	No Recurrence (n, %)	P value
Men	8 (6.20%)	121 (93.80%)	0.788
Women	7 (6.25%)	85 (93.75%)
Age ≤ 65 years	7 (7.22%)	90 (92.78%)	1.00
Age > 65 years	8 (6.45%)	116 (93.55%)
Pathological stage I	0 (0.00%)	48 (100%)	0.063
Pathological stage II	7 (9.86%)	64 (90.14%)
Pathological stage III	8 (7.84%)	93 (92.16%)
Adjuvant CT (-)	6 (5.36%)	106 (94.64%)	0.433
Adjuvant CT (+)	9 (8.26%)	100 (91.74%)
Neoadjuvant CCRT (-)	13 (6.46%)	178 (93.54%)	0.243
Neoadjuvant CCRT (+)	3 (9.68%)	28 (90/32%)
Pathological tumor size < 5 cm	4 (2.78%)	139 (97.22%)	0.003
Pathological tumor size ≥ 5 cm	11 (14.10%)	67 (85.90%)
Adjuvant RT (-)	9 (4.46%)	193 (95.57%)	0.001
Adjuvant RT (+)	6 (31.58%)	13 (68.42%)
APR (-)	9 (4.46%)	193 (95.57%)	0.001
APR (+)	6 (31.58%)	13 (68.42%)
Upper-third rectum	0 (0.00%)	56 (100%)	0.003
Middle-third rectum	5 (7.65%)	93 (93.35%)
Lower-third rectum	10 (14.93%)	57 (85.07%)
WD adenocarcinoma	2 (4.65%)	41 (95.35%)	0.046
MD adenocarcinoma	12 (6.90%)	162 (93.10%)
PD adenocarcinoma	1 (50.00%)	1 (50.00%)
LVI negative	6 (4.58%)	125 (95.42%)	0.150
LVI positive	8 (10.39%)	69 (89.61%)
CRM negative	10 (5.00%)	190 (95.00%)	0.052
CRM positive	6 (28.57%)	15 (71.43%)
Pathological T1-3	12 (5.71%)	198 (94.29%)	0.016
Pathological T4	3 (27.27%)	8 (72.73%)
Pathological N0	9 (7.14%)	117 (92.86%)	1.0
Pathological N1-2	6 (6.32%)	89 (93.68%)

APR, abdominal perineal resection; RT, radiotherapy; CT, chemotherapy; CRM: circumferential margin; WD, well-differentiated; MD, moderately differentiated; PD, poorly differentiated; LVI, lymphatic vascular invasion; CCRT, concurrent chemoradiotherapy