Table 3.

Association between baseline characteristics and overall survival

			Univariate analysis		Multivariate analysis
		Survival, mo (95% CI)a	HR (95% CI)	P	HR (95% CI)	P
Age, y	<65	20.01 (18.70–21.32)	1		1
	≥65	18.90 (17.60–21.20)	1.24 (0.89–1.74)	0.206	0.98 (0.69–1.40)	0.922
Gender	Female	20.61 (19.35–21.86)	1		1
	Male	18.12 (16.81–19.43)	1.41 (1.01–1.96)	0.045	1.55 (1.07–2.24)	0.021
Histology	Adenocarcinoma	19.88 (18.57–21.19)	1		1
	Squamous	18.97 (17.69–20.25)	1.29 (0.92–1.82)	0.138	1.29 (0.88–1.89)	0.185
Cancer stage	IIIB	21.81 (19.89–23.74)	1		1
	IV	18.60 (17.59–19.61)	1.73 (1.18–2.52)	0.005	1.36 (0.92–2.02)	0.127
CCI score	<9	20.84 (19.52–22.17)	1		1
	≥9	17.80 (16.64–18.96)	1.14 (1.07–1.21)	<0.001	1.10 (1.02–1.17)	0.009
Smoking status	Nonsmoker	21.41 (19.82–22.99)	1		1
	Smoker	18.10 (17.07–19.12)	2.07 (1.46–2.95)	<0.001	1.52 (1.02–2.26)	0.042

^aMedian