REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
goat anti-human Fab secondary antibody	Thermo Scientific Pierce	Cat # PA5-33290
Bacterial and Virus Strains
E. coli BL21 Gold(DE3) cells	Agilent	Cat# 230132
HEK 293T cells	ATCC	ATCC 11268
TZM-bl cells	NIH ARRRP	NIH ARRRP 8129
Chemicals, Peptides, and Recombinant Proteins
BanLec	This paper	N/A
gp120 (JR-CSF & Bal)	This paper	N/A
TEV protease	This paper	N/A
Ampicillin	Sigma-Aldrich	Cat# A0166
Kanamycin	Sigma-Aldrich	Cat# K1377
anthranliamide	Sigma-Aldrich	Cat# A89804
ammonium acetate	Sigma-Aldrich	Cat# A2706
IPTG	Sigma-Aldrich	Cat# I5502
kifunensine	Sigma-Aldrich	Cat# K1140
Protease inhibitor cocktail	Roche	Cat# 05056489001
luciferase substrate	Promega	Cat# E1500
PNGase F	New England BioLabs	Cat# P0705S
Critical Commercial Assays
Phusion High-Fidelity PCR kit	New England BioLabs	Cat# E0553
Qiagen Gel Extraction kit	Qiagen	Cat# 28704
In-Fusion HD Cloning Kit	Clontech	Cat# 639648
Deposited Data
BanLec dimer	This paper	PDB: 5EXG
Oligonucleotides
Primers for BanLec D38G Forward: GTGACATCAACACCGCCAACCACATCGCCAC Reverse: GTGGCGATGTGGTTGGCGGTGTTGATGTCAC	This paper	N/A
Primers for BanLec D133G Forward: GATAGACACCAATGGCACCCAGGAATTTACCACCA Reverse: TGGTGGTAAATTCCTGGGTGCCATTGGTGTCTATC	This paper	N/A
Primers for BanLec H84T Forward: TGCTAACTACACCGGTGCGGTCGTGC Reverse: ACTTCACCTGCCATGCCC	This paper	N/A
Primers for BanLec Y46K Forward: Forward: CACCTTCACGAAATACGGCAAAAC Reverse: ACATCAACACCGTCAACC	This paper	N/A
REAGENT or RESOURCE	SOURCE	IDENTIFIER
Recombinant DNA
BanLec template DNA	Clonetech (based on Peumans et al., 2000)	N/A
Plasmid: pET28b	Merck-Millipore	Cat# 69864
Software and Algorithms
UniDec	Marty et al., 2015	unidec.chem.ox.ac.uk.
Empower 3.0	Waters	N/A
Masslynx v4.1	Waters	N/A
Astra 6.1 software	Wyatt Technologies	N/A
ATSAS	Svergun et al., 2001	https://www.embl-hamburg.de/biosaxs/software.html
Situs	Wriggers and Chacon, 2001	http://situs.biomachina.org/fguide.html
Coot	Emsley et al., 2010	http://www.ccp4.ac.uk/
Phaser	McCoy et al., 2007	http://www.phaser.com/
Impact	Marklund et al., 2015	http://impact.chem.ox.ac.uk/
GLYCAM-Web	Kirschner et al., 2008	www.glycam.org
Amber14SB	Case et al., 2014	http://ambermd.org/
Other
HisTrap HP column	GE Healthcare	Cat# 17-5248-02
Superose 6 Increase 10/300 column	GE Healthcare	Cat# 29-0915-96
Vivaspin 5000 MWCO filter	GE Healthcare	Cat# 28932223
SDS-PAGE gel	Novex NuPAGE	Cat# NW04120
Microtitre ELISA plates	Corning	Cat# 3369
LudgerSep N2 amide HPLC column	Ludger Ltd.	Cat# LS-N2-4.6x150
Bio SEC-3 SEC column	Agilent	Cat# 5190-2504
Bio-spin 6 centrifuge columns	Bio-Rad	Cat# 7326221