Table 2. Determination of MICs and MBCs in μg/ml in M. smegmatis mutants.
| 2058A | 2058A→G | 2058A→G | 2058A→G | |
|---|---|---|---|---|
| 2057A | 2057A | 2057A→G | 2057A→G | |
| Drug | 2611U | 2611U | 2611U | 2611U→C |
| Telithromycin | ||||
| MIC | 0.25-0.5 | 64-128 | 128-256 | 4-8 |
| MBC | 8 | >512 | >512 | 64-128 |
| Erythromycin | ||||
| MIC | 16 | >512 | >512 | >512 |
| MBC | 256 | >512 | n.d. | >512 |
| Clarithromycin | ||||
| MIC | 0.5 | >512 | >512 | >512 |
| MBC | 8 | >512 | n.d. | >512 |
| Azithromycin | ||||
| MIC | 8 | >512 | >512 | >512 |
| MBC | 32 | >512 | n.d. | >512 |
| Tylosin | ||||
| MIC | 8 | 32 | 32-64 | 32 |
| MBC | 64 | 256 | n.d. | 256 |
| Spiramycin | ||||
| MIC | 16 | 128-256 | 256 | 128-256 |
| MBC | 256 | 512 | n.d. | 512 |
| Josamycin | ||||
| MIC | 2 | 16 | 32 | 16 |
| MBC | 32 | 64 | n.d. | 64 |
n.d., not done.