Table 4.
Summary of best response to therapy
| Best Response | Tosedostat 120 mgN=38 N (%) |
Tosedostat 240 mg→120 mg N=35 N (%) |
Overall N=73 N (%) |
|---|---|---|---|
|
| |||
| PR or better | 8 (21) | 8 (23) | 16 (22) |
|
| |||
| CR | 0 | 1 (3) | 1 (1) |
| CRp | 2 (5) | 4 (11) | 6 (8) |
| MLFS | 2 (5) | 0 | 2 (3) |
| PR | 4 (11) | 3 (9) | 7 (10) |
| SD | 14 (37) | 7 (20) | 21 (29) |
| PD | 6 (16) | 7 (20) | 13 (18) |
| Non-evaluable | 10 (26) | 13 (37) | 23 (32) |
CR=complete remission; CRp=complete remission with incomplete platelet recovery; MLFS=morphological leukaemia-free state; PR=partial remission; SD=stable disease; PD=progressive disease;