Table 4.

Adjusted analysis by multiple logistic regression of increase in degree of frailty until follow-up (3 months)

	OR (95% CI)	P-value
Clinic
CGA unit (intervention group)	0.229 (0.131–0.400)	<0.0001
Conventional care (control group)	REF
Sex
Female	0.864 (0.509–1.467)	0.588
Male	REF
Age	0.996 (0.950–1.045)	0.876
Charlson Comorbidity Index score	0.995 (0.842–1.175)	0.951

Notes: Increase in frailty refers to a minimum one-step increase on the FRESH frailty instrument. OR indicates odds ratio. Patients were excluded from the analysis if information of frailty score was missing at index and/or follow-up. Age, sex, and Charlson Comorbidity Index score were potential confounders and used as covariates. They were tested for collinearity with the use of the variance inflation factor. All variables had a variance inflation factor value <2.5, which does not indicate collinearity.

Abbreviations: FRESH, FRail Elderly Support researcH group; REF, reference.