Table 1.
Baseline characteristics of study participants
| Non-COPD (N=2,542) |
COPD (N=421) |
P-value | |
|---|---|---|---|
| Age | 56.4±10.3 | 65.4±8.8 | <0.001 |
| Male sex | 992 (39.0) | 317 (75.3) | <0.001 |
| Height, cm | 160.9±8.7 | 164.5±8.6 | <0.001 |
| BMI, kg/m2 | 24.3±3.1 | 23.9±2.8 | 0.01 |
| Current smoker | 344 (13.7) | 111 (27.2) | <0.001 |
| Waist circumference, cm | 83.5±8.9 | 86.1±8.3 | <0.001 |
| Hypertension | 722 (28.4) | 172 (40.9) | <0.001 |
| Diabetes | 246 (9.7) | 68 (16.2) | <0.001 |
| MI/angina | 73 (3.0) | 22 (5.4) | 0.01 |
| Depression | 139 (5.5) | 15 (3.6) | 0.16 |
| Pulmonary function test | |||
| FVC, L | 3.45±0.84 | 3.68±0.91 | <0.001 |
| FVC, % predicted | 93.3±11.2 | 91.1±14.2 | 0.002 |
| FEV1, L | 2.73±0.66 | 2.35±0.64 | <0.001 |
| FEV1, % predicted | 94.9±11.6 | 79.9±15.3 | <0.001 |
| FEV1/FVC, % | 79.4±4.7 | 63.9±6.3 | <0.001 |
| Hand grip strength, kg | 29.9±9.5 | 33.3±9.1 | <0.001 |
| EQ-5D index | 0.94±0.11 | 0.92±0.13 | <0.001 |
| Mobility | 1.49±1.65 | 1.51±1.46 | 0.77 |
| Self-care | 1.38±1.64 | 1.33±1.45 | 0.53 |
| Daily activity | 1.43±1.64 | 1.39±1.45 | 0.64 |
| Pain/discomfort | 1.61±1.66 | 1.58±1.47 | 0.71 |
| Anxiety/depression | 1.46±1.65 | 1.38±1.46 | 0.36 |
Note: Data shown as mean ± standard deviation and n (%).
Abbreviations: BMI, body mass index; MI, myocardial infarction; FVC, forced vital capacity; FEV1, forced expiratory volume in 1 second; EQ-5D, EuroQOL5-item questionnaire.