Table 2.
Clinical characteristics of patients at both settings
| Characteristics | PC N=294 |
Pulm N=353 |
P-value |
|---|---|---|---|
| Sex, % men | 77.9 | 83.3 | 0.08 |
| Age, mean (SD) | 68.5 (9.2) | 67.9 (9.1) | 0.40 |
| BMI kg/m2, mean (SD) | 27.7 (4.3) | 27.1 (4.7) | 0.09 |
| Current smoker, % | 36.0 | 20.4 | <0.0001 |
| Dyspnea on exertion, % | 84.7 | 90.9 | 0.02 |
| Sputum production, % | 72.1 | 51.8 | <0.0001 |
| Wheezing, % | 48.3 | 29.7 | <0.0001 |
| Chronic cough, % | 85.3 | 66.8 | <0.0001 |
| FEV1 postbr, mL, mean (SD) | 1,637 (588) | 1,416 (551) | <0.0001 |
| FEV1 postbr, %, mean (SD) | 56.4 (20.7) | 50.5 (16.8) | <0.0001 |
| BODEx index, mean (SD) | 3.2 (1.9) | 3.4 (2.0) | 0.19 |
| COTE index, mean (SD) | 1.4 (2.2) | 1.2 (1.9) | 0.15 |
| Mod/Sev Exac prev year, mean (SD) | 2.2 (1.8) | 1.6 (1.8) | <0.0001 |
| CAT score, mean (SD) | 19.5 (8.3) | 14.9 (7.8) | <0.0001 |
| CDLM score, mean (SD) | 1.3 (0.5) | 1.2 (0.4) | <0.001 |
| LABA + LAMA (free or fixed dose combination), % | 25.6 | 25.9 | 1 |
| LABA + LAMA + ICS (free combination), % | 42.9 | 52.4 | 0.0177 |
Note: Categorical variables: Fisher’s exact test, two-tailed P-value; continuous variables: Student’s t-test.
Abbreviations: BMI, body mass index; BODEx, body mass index, airflow obstruction, dyspnea, and exercise capacity index; CAT, COPD assessment test; CDLM, Capacity of Living during the Morning questionnaire; COTE, COPD specific comorbidity test; ICS, inhaled corticosteroids; LABA, long-acting beta-agonist; LAMA, long-acting antimuscarinic; m-MRC, modified Medical Research Council dyspnea scale; FEV1, forced expiratory volume in 1 s; FEV1 (%), percentage of predicted FEV1; PC, primary care; Pulm, pulmonology; SD, standard deviation; postbr, post-bronchodilator; Mod/Sev Exac prev, moderate/severe exacerbations previous year.