Table 1.
Characteristics of the datasets
| Dataset
|
ADNI
|
NACC
|
TMUGHR
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| Diagnosis | NC | MCI | AD | NC | MCI | Dementia | NC | MCI | AD |
|
|
|
|
|
||||||
| N | 311 | 486 | 153 | 385 | 186 | 151 | 120 | 30 | 20 |
| Age (years) | 73.4±6.3 | 71.7±7.5 | 74.8±8.2 | 70.3±10.9 | 75.4±7.7 | 75.7±7.9 | 61.6±9.6 | 66.3±8.3 | 66.1±6.6 |
| Female (%) | 54.0 | 45.7 | 42.5 | 66.0 | 35.5 | 42.4 | 60.8 | 60.0 | 55.0 |
| Education (years) | 16.6±2.5 | 16.2±2.7 | 15.8±2.1 | 16.0±2.7 | 15.5±2.8 | 14.9±3.1 | 13.5±3.4 | 12.0±3.5 | 10.2±3.9 |
| CDR (0–3) | 0.0±0.0 | 0.5±0.0 | 0.8±0.3 | 0.0±0.1 | 0.2±0.1 | 0.4±0.2 | 0.0±0.1 | 0.2±0.2 | 0.6±0.2 |
| MMSE (0–30) | 29.0±1.3 | 28.0±1.7 | 23.1±2.1 | 29.1±1.2 | 26.4±2.5 | 20.6±5.0 | 28.8±1.0 | 27.0±0.5 | 24.3±2.0 |
Note: Data are presented as mean ± SD, unless otherwise as indicated.
Abbreviations: AD, Alzheimer’s disease; ADNI, Alzheimer’s disease neuroimaging initiative; CDR, clinical dementia rating; MCI, mild cognitive impairment; MMSE, Mini-Mental State Examination; N, number of subjects; NACC, National Alzheimer’s Coordinating Center; NC, normal cognition; TMUGHR, Tianjin Medical University Research dataset.