Table 3.
Correlation coefficients between sequence pairs for the Brain Atrophy and Lesion Index (BALI) total score
| T1WI | T2WI | T2-FLAIR | T2*GRE | Combineda | |
|---|---|---|---|---|---|
| T1WI | 1 | 0.94 | 0.83 | 0.86 | 0.90 |
| T2WI | 1 | 0.86 | 0.87 | 0.94 | |
| T2-FLAIR | 1 | 0.89 | 0.86 | ||
| T2*GRE | 1 | 0.86 | |||
| Combineda | 1 |
Notes:
a
The combined total score was constructed by integrating categorical scores evaluated using multiple MRI sequences: T2WI for GMSV, BG, IT, and others; T2-FLAIR for DWM and PV; T1WI for GA; and GRE for hemorrhage. For each test, n=170; level of significance P<0.00001.
Abbreviations: T1WI, T1-weighted imaging; T2WI, T2-weighted imaging; T2-FLAIR, T2-weighted fluid atten uation inversion recovery sequence; T2*GRE, T2*-weighted gradient recalled echo sequence.