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HNP-1 protects macrophages against B. anthracis-induced cell death. (a) RAW 264.7 cells were infected with B. anthracis spores and then treated with the indicated amounts of HNP-1. Cytotoxicity was determined by measuring released lactate dehydrogenase levels. (b)An in vitro killing assay was performed against spores in the presence or absence of 1 μM HNP-1. After the indicated incubation times, colony-forming units (CFU) were determined.
