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. 2017 Aug;67(4):300–314.

Table 3.

Histologic characteristics of PDOX tumors

					Tumor location
	Hypercellularity	PP necrosis	Necrosis without PP	Thrombosis	Subcortical	Cortical	White matter
GBM1
Ventricular (n = 5)	2.8 ± 0.60	1.20 ± 1.09	0.90 ± 0.98	0.85 ± 0.89	0.95 ± 0.98	1.15 ± 0.82	2.20 ± 1.02
Nonventricular (n = 10)	3.20 ± 0.33	1.73 ± 1.00	2.41 ± 1.06	2.43 ± 1.46	3.25 ± 1.14	2.98 ± 1.02	2.72 ± 0.86
P	0.1983	0.5388	0.0726	0.0193^a	0.0073^a	0.0142^a	0.4898
GBM2
Ventricular (n = 6)	3.38 ± 0.14	0.42 ± 0.38	0.25 ± 0.61	0.17 ± 0.30	1.08 ± 1.02	0.38 ± 0.70	1.25 ± 0.71
Nonventricular (n = 10)	3.65 ± 0.13	0.98 ± 0.71	1.03 ± 1.43	1.25 ± 1.24	3.93 ± 0.12	3.2 ± 0.69	2.95 ± 0.71
P	0.0083^a	0.1036	0.0031^a	0.0140	0.0006^b	0.0002^b	0.0023^a
GBM3
Ventricular (n = 9)	2.03 ± 1.53	0.03 ± 0.08	0.17 ± 0.50	0.47 ± 0.90	0.44 ± 0.67	0.14 ± 0.33	0.59 ± 0.76
Nonventricular (n = 5)	3.22 ± 1.4	1.9 ± 1.31	1.42 ± 0.94	2.9 ± 0.72	3.31 ± 0.43	3.14 ± 0.67	2.31 ± 0.91
P	0.0879	0.0008^b	0.0306^a	0.0064^a	<0.0001^c	<0.0001^c	0.0024^a
GBM4
Ventricular (n = 4)	3.25 ± 0.01	0.0 0 ± 0.00	1.81 ± 1.38	0.50 ± 1.00	0.63 ± 0.95	0.38 ± 0.75	0.50 ± 1.00
Nonventricular (n = 6)	3.50 ± 0.22	2.21 ± 1.20	2.21 ± 0.75	0.79 ± 0.93	3.75 ± 0.50	2.79 ± 1.59	3.21 ± 0.76
P	0.0892	0.0069^a	0.5678	0.6489	0.0004^b	0.0012^a	0.0012^a

PP, pseudopalisading

Data are given as mean ± 1 SD.

^a

P < 0.05 (Unpaired t test)

^b

P < 0.001 (Unpaired t test)

^c

P < 0.0001 (Unpaired t test)