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. 2017 Aug;67(4):335–343.

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Figure 5. — Return to normal T1D incidence after SFB elimination and microbiome reconstitution. (A) Incidence curves for T1D development in female NOD/ShiLtDvs mice in 2001 (n = 20), 2003 (n = 43), 2007 (n = 21), 2008–2009 (n = 20), and 2010 (n = 18) showing approximately 75% to 95% incidence by 30 wk of age. (B) After eliminating SFB from the NOD colony in 2015, T1D development in female mice returned to an incidence (approximately 85% by 30 wk of age; n = 18) consistent with that historically observed.