Table 4. Sequences of the Rhodopsin, CXCR4, and β1AR Receptor Helices Used in Ensemble Simulation Sets.
| receptor | helices | sequencesa |
|---|---|---|
| rhodopsin | TM1 | QFSMLAAYMFLLIMLGFPIN1.50(55)FLTLYVTVQ |
| TM2 | NYILLNLAVAD2.50(83)LFMVFGGFTTTLYTSLH | |
| TM4 | ENHAIMGVAFTW4.50(161)VMALACAAPPL | |
| TM5 | NESFVIYMFVVHFIIP5.50(215)LIVIFFCYGQ | |
| CXCR4 | TM5 | VVVFQFQHIMVGLILP5.50(211)GIVIL |
| TM6 | VILILAFFACWLP6.50(254)YYIGISI | |
| β1AR | TM1 | QWEAGMSLLMALVVLLIVAGN1.50(59)VLVIAAIG |
| TM2 | NLFITSLACAD2.50(87)LVMGLLVVPFGATLVV | |
| TM4 | ARAKVIICTVW4.50(166)AISALVSFLPIMM | |
| TM5 | AYAIASSIISFYIP5.50(219)LLIMIFVYLRVY |
a
The conserved amino acid for each TM helix is shown in italics and is numbered using both the Ballesteros and Weinstein nomenclature (superscript) and by residue number.